One of the most revealing and difficult questions from the point of view of the implementation of maintaining the health of astronauts is the question of developing the correct regime of life and nutrition in order to most effectively combat active loss of muscle mass, which quite often happens. aboard the ISS and, in principle, in space. Of course, at the moment, absolutely all space missions use a set of special exercises aimed at maintaining the muscle mass of astronauts at the proper level, but today a team of NASA researchers presented the results of one interesting project in this area.
The fact is that earlier the attention of the research group was focused on the study and analysis of the so-called MSTN protein or myostatin, as it is called in medicine вЂ” this protein is a special regulator of muscle mass, which, on the one hand, prevents it from growing and developing uncontrollably, and on the other hand actively invests in its growth. In normal terrestrial conditions, it works as it should, but in space, everything takes on a slightly more problematic shade.
That is why NASA specialists previously launched 40 experimental mice into space aboard a SpaceX-19 rocket, which were subsequently observed and received various inhibitors that regulate the production of this protein. When the mice returned to Earth, the researchers were able to identify the most promising candidate for an ACVR2B / Fc inhibitor, which allowed the mice to retain 18% more muscle mass than mice treated with other inhibitors.
It is worth noting that blocking myostatin, for its part, also represents a rather promising approach to solving the problem of maintaining muscle mass in space вЂ” however, this result is achieved only in combination with third-party chemicals. Be that as it may, at the moment it remains only to wait for the continuation of the study, which is likely to offer conceptually different approaches to maintaining a large amount of muscle mass in space.